Abstract:

Pain, including persistent chronic pain, not only has a strong negative affection but is also intimately related to fear, anxiety and depression. The amygdala is believed to be a key subcortical structure involved in emotional affective behavior including the emotional responses to pain. Our recent studies show the evidence that amygdala plays a key role in pain and pain-related affective and cognitive disorders. 

Key words:  amygdala; pain; anxiety; cognitive impairment