J4 ›› 2011, Vol. 46 ›› Issue (10): 171-177.

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The role of amygdala in pain and pain-related affective and cognitive disorders

JI Guang-chen   

  1. Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555, USA
  • Received:2011-06-01 Online:2011-10-20 Published:2011-10-18
  • About author:Guangchen Ji Ph. D. (1965 ), Male, his research mainly focuses on neurobiological mechanism of pain. Email:guji@utmb.edu


Pain, including persistent chronic pain, not only has a strong negative affection but is also intimately related to fear, anxiety and depression. The amygdala is believed to be a key subcortical structure involved in emotional affective behavior including the emotional responses to pain. Our recent studies show the evidence that amygdala plays a key role in pain and pain-related affective and cognitive disorders. 

Key words:  amygdala; pain; anxiety; cognitive impairment

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