杏仁核在疼痛及疼痛引起的情感和认知障碍中的作用

J4 ›› 2011, Vol. 46 ›› Issue (10): 171-177.

杏仁核在疼痛及疼痛引起的情感和认知障碍中的作用

姬广臣

美国德州大学医学部神经科学和细胞生物学系，德克萨斯州加尔维斯顿 77555

收稿日期:2011-06-01 出版日期:2011-10-20 发布日期:2011-10-18

The role of amygdala in pain and pain-related affective and cognitive disorders

JI Guang-chen

Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555, USA

Received:2011-06-01 Online:2011-10-20 Published:2011-10-18
About author:Guangchen Ji Ph. D. (1965 ), Male, his research mainly focuses on neurobiological mechanism of pain. Email:guji@utmb.edu

摘要/Abstract

摘要：

疼痛是一种不愉快的感觉和情绪体验, 伴随有强烈的负性情绪(如厌恶、恐惧、焦虑等)。杏仁核作为边缘系统的皮质下中枢，在情绪反应中具有重要作用。我们的研究表明杏仁核在疼痛调制，特别是疼痛情绪反应中起关键作用。本文综述了杏仁核在疼痛及疼痛引起的焦虑行为和认知功能障碍中的作用。

关键词: 杏仁核；疼痛；焦虑；认知障碍　

Abstract:

Pain, including persistent chronic pain, not only has a strong negative affection but is also intimately related to fear, anxiety and depression. The amygdala is believed to be a key subcortical structure involved in emotional affective behavior including the emotional responses to pain. Our recent studies show the evidence that amygdala plays a key role in pain and pain-related affective and cognitive disorders.

Key words: amygdala; pain; anxiety; cognitive impairment

姬广臣. 杏仁核在疼痛及疼痛引起的情感和认知障碍中的作用[J]. J4, 2011, 46(10): 171-177.

JI Guang-chen. The role of amygdala in pain and pain-related affective and cognitive disorders[J]. J4, 2011, 46(10): 171-177.

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