J4 ›› 2009, Vol. 44 ›› Issue (7): 71-78.

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Modeling in fedbatch fermentation and its parameter 
identification based on HPSO algorithm

GONG Zhaohua1,2, LIU Chongyang1, FENG Enmin2   

  1. 1. School of Mathematics and Information Science, Shandong Institute of Busines s and Technology, Yantai 264005, Shandong, China; 2. School of  Mathematics, Dalian University of Technology, Dalian 1 16024, Liaoning, China
  • Received:2008-12-15 Online:2009-07-16 Published:2009-11-01
  • About author:GONG Zhaohua(1978-), female, Ph.D. candidate, major in operational research and control theory. Email: yt-gzh@yahoo.com.cn
  • Supported by:

    Supported by National Science Foundatio

    n of Ch

    ina (10871033, 10671126) and National Basic Research Program of China (2007AA02Z

    208)

Abstract:

Modeling and its parameter identification are investigated in glycerol bioconversion to 1,3propanediol (1,3PD) by Klebsiella pneumoniae (K.pneumoniae) in fedbatch cultures. Considering the discontinuity of adding glyceroland alkali in the process, a nonlinear multistage dynamical system is presented to formulate the process. Taking the minimal errors between the experimental data and calculated values as the performance index, we propose an identification model and prove the existence of optimal kinetic parameters. Finally, a hybridparticle swarm optimization (HPSO) algorithm is constructed to solve the identification model. Numerical results show that the error is reduced by 176%~4177% and the proposed dynamical system can better formulate the fedbatch culture.

Key words: modeling; parameter identification; particle swarm optimizati on; 1,3propanediol; fedbatch fermentation

CLC Number: 

  • O17514
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