JOURNAL OF SHANDONG UNIVERSITY(NATURAL SCIENCE) ›› 2015, Vol. 50 ›› Issue (01): 81-84.doi: 10.6040/j.issn.1671-9352.0.2014.198

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Solute transport in articular cartilage under rolling-compressing load

WANG Long-tao1,2, YANG Xiu-ping1,2, LIU Qing2, YANG Wen-jing3, FAN Zhen-min2, ZHANG Chun-qiu2   

  1. 1. Tianjin Key Laboratory of the Design and Intelligent Control of the Advanced Mechatronical System, Tianjin 300384, China;
    2. School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China;
    3. Pharmacy Department, Tianjin Worker's Hospital, Tianjin 300005, China
  • Received:2014-05-04 Revised:2014-10-22 Online:2015-01-20 Published:2015-01-24

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Abstract: In order to study solute transport behavior of articular cartilage under rolling-compressing load, mature pig articular cartilages were marked by Fluorescein isothiocyanate-Dextran, their solute fluorescence intensity change with time and cartilage depth was observed under rolling-compressing load and static state respectively. The changing laws of relative concentration and diffusivity were obtained. The results show that solute relative concentration under rolling-compressing load (sample B) is larger than that under static state (sample A), and average maximum is 62.4% difference. Relative concentration in transitional and deep layers of sample B increases more significantly than that of sample A with time increasing. Diffusivity of sample B is larger than that of sample A, and average maximum is 93% difference. Diffusivity in transitional and deep layer of sample B increases more conspicuously than that of sample A with time increasing. So rolling-compressing load can promote solute transport, and improve solute diffusivity in articular cartilage, especially in transitional and deep layers.

Key words: diffusivity, rolling-compressing load, solute, articular cartilage, concentration

CLC Number: 

  • R318.01
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